Technical Brief

Genomics Tech Brief- HPE, NVIDIA, WEKA

The HPE Apollo 6500 Gen10 System with a WekaIO (Weka) flash-optimized parallel file system on HPE ProLiant DL360 Gen10 Servers enables the high-throughput execution of secondary genomic analyses using the NVIDIA® Parabricks Germline Pipeline. The NVIDIA Parabricks Germline Pipeline accelerates the Broad Institute’s original GATK Best Practices pipeline using NVIDIA GPUs, while the WekaIO File System (WekaFS™) delivers the file I/O performance necessary to keep each GPU fully loaded with genomic data and metadata. This performance scales with high efficiency in order to support large multinode GPU clusters, thereby reducing time to solution and increasing productivity.